Carbapenems vs alternative antibiotics for the treatment of complicated urinary tract infection: a systematic review and network meta-analysis
X Tan, Q Pan, C Mo, X Li, X Liang, Y Li, Y Lan, L Chen - Medicine, 2020 - journals.lww.com
Background: Complicated urinary tract infections (cUTI) are universal reasons for
hospitalization, and highly likely to develop into sepsis or septic shock. Carbapenem
antibiotics with potentially higher efficacy or with fewer and milder side effects have
increased in popularity, but evidence is limited by a scarcity of randomized controlled trials
(RCTs) comparing different carbapenem antibiotics for cUTI. Network meta-analysis is a
useful tool to compare multiple treatments when there is limited or no direct evidence …
hospitalization, and highly likely to develop into sepsis or septic shock. Carbapenem
antibiotics with potentially higher efficacy or with fewer and milder side effects have
increased in popularity, but evidence is limited by a scarcity of randomized controlled trials
(RCTs) comparing different carbapenem antibiotics for cUTI. Network meta-analysis is a
useful tool to compare multiple treatments when there is limited or no direct evidence …
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